

About me
My undergraduate education is in theoretical physics at Lund University. During my degree projects, I have worked on analyzing experimental data within biophysics.
About my research
Quantitative studies of biological processes are often interdisciplinary in nature. In the analysis of such a study, simulations, modelling and calculations are required. By improving the description of underlying processes, the analysis may be optimized. With these methods, I seek to estimate the binding parameters of T-cell receptors from fluorescence microscopy movies.
There are a number of challenges in this analysis. For instance, it is unknown which of the tracked proteins are bound or free, how random camera noise affects the movies, and which fluorescent dots are to be linked from one frame to the next. To find the most probable solutions to these problems, I do probabilistic calculations in a Bayesian framework.
Publications
Displaying of publications. Sorted by year, then title.
Achieving subtemporal resolution in the analysis of two-state single-molecule trajectories
Erik Clarkson, Tobias Ambjörnsson
(2026) Physical Review Research, 8 p.013115-013115
Journal articlePhotophysical image analysis for sCMOS cameras: Noise modelling and estimation of background parameters in fluorescence-microscopy images
Dibyajyoti Mohanta, Radhika Kunnath, Erik Clarkson, Albertas Dvirnas, Fredrik Westerlund, et al.
(2025) PLOS ONE, 20
Journal articleBayesian and frequentist analyses of two-state single-molecule diffusion trajectories
Erik Clarkson, Tobias Ambjörnsson
(2025) Journal of Physics A: Mathematical and Theoretical, 58
Journal article

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