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Computational biophysics

In the field of computational biophysics, we mainly study the behaviour of large molecules such as proteins, DNA and RNA. Using tools from statistical and computational physics, we construct models and investigate biomolecular processes and properties.

We are particularly interested in membrane-less organelles, protein aggregation and how molecular crowding affects protein properties. The properties of molecules are often studied in aqueous solution, but less is known about their behaviour in living cells. Much of this research is based on detailed thermodynamic simulations of protein chains in purpose-built software, but we also work with more coarse-grained models. Some of our research is performed in collaboration with experimental groups.

We also investigate the possibility of using quantum computers to solve biomolecular problems. As a first demonstration, we have calculated the structure of proteins in a simple lattice-based model on a quantum computer.

The group is part of COSHE, the Computational Science for Health and Environment theme at CEC.

Group leader

Anders Irbäck
E-mail: anders [dot] irback [at] cec [dot] lu [dot] se (anders[dot]irback[at]cec[dot]lu[dot]se)
Phone: +46 46 222 34 93

Involved researchers

All links go to the Lund University Research Portal.