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Photo of Victor Olariu

Victor Olariu

Senior lecturer

Photo of Victor Olariu

Modelling Stem Cells Lineages with Markov Trees

Author

  • Victor Olariu
  • Daniel Coca
  • Stephen A. Billings
  • Visakan Kadirkamanathan

Summary, in English

A variational Bayesian EM with smoothed probabilities algorithm for hidden Markov trees (HMT) is proposed for incomplete tree structured data. The full posterior of the HMT parameters is determined and the underflow problems associated with previous algorithms are eliminated. Example results for the prediction of the types of cells in real stem cell lineage trees are presented.

Publishing year

2009-10-16

Language

English

Pages

233-243

Publication/Series

Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)

Volume

5780 LNBI

Document type

Conference paper

Conference name

4th IAPR International Conference on Pattern Recognition in Bioinformatics, PRIB 2009

Conference date

2009-09-07 - 2009-09-09

Conference place

Sheffield, United Kingdom

Status

Published

ISBN/ISSN/Other

  • ISSN: 1611-3349
  • ISSN: 0302-9743
  • ISBN: 3642040306
  • ISBN: 9783642040306