Tobias Ambjörnsson
Universitetslektor
Sensing DNA–DNA as Nanosensor: A Perspective Towards Nanobiotechnology
Författare
Summary, in English
Based on modern single molecule techniques, we devise a number of possible experimental setups to probe local properties of DNA such as the presence of DNA-knots, loops or folds, or to obtain information on the DNA-sequence. Similarly, DNA may be used as a local sensor. Employing single molecule fluorescence methods, we propose to make use of the physics of DNA denaturation nanoregions to find out about the solvent conditions such as ionic strength, presence of binding proteins, etc. Bymeasuring dynamical quantities in particular, rather sensitive nanoprobes may be constructed with contemporary instruments.
Publiceringsår
2005-09-01
Språk
Engelska
Sidor
389-395
Publikation/Tidskrift/Serie
Journal of Computational and Theoretical Nanoscience
Volym
2
Issue
3
Länkar
Dokumenttyp
Artikel i tidskrift
Förlag
American Scientific Publishers
Ämne
- Physical Chemistry
- Biophysics
- Other Physics Topics
Status
Published
ISBN/ISSN/Övrigt
- ISSN: 1546-1955